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Publications in Journals

Modelling Approach for the Continuous Biocatalytic Synthesis of N-Acetylneuraminic Acid in Packed Bed Reactors

Hölting, K., Aßmann, M., Bubenheim, P., Liese, A., & Kuballa, J.
Processes, 2024
https://doi.org/10.3390/pr12102191

Resilient Enzymes through Immobilisation: Stable NDP Polyphosphate Phosphotransferase from Ruegeria pomeroyi for Nucleotide Regeneration

Hölting, K., Götz, S., Aßmann, M., Bubenheim, P., Liese, A., & Kuballa, J.
Catalysts, 2024
https://doi.org/10.3390/catal14030165

Modular bioengineering of whole-cell catalysis for sialo-oligosaccharide production: coordinated co-expression of CMP-sialic acid synthetase and sialyltransferase

Schelch, S., Eibinger, M., Zuson, J., Kuballa, J., & Nidetzky, B.
Microbial Cell Factories, 2022
https://doi.org/10.1186/s12934-023-02249-1

Immobilization of CMP‐Sialic Acid Synthetase and α2,3‐Sialyltransferase for Cascade Synthesis of 3′‐Sialyl β‐D‐Galactoside with Enzyme Reuse

Schelch, S., Koszagova, R., Kuballa, J., & Nidetzky, B.
ChemCatChem, 2022
https://doi.org/10.1002/cctc.202101860

Shift of reaction equilibrium at high pressure in the continuous synthesis of neuraminic acid

Reich, J. A., Aßmann, M., Hölting, K., Bubenheim, P., Kuballa, J. & Liese, A.
Beilstein, 2022
https://doi.org/10.3762/bxiv.2022.11.v1

Repetitive Synthesis of High‐Molecular‐Weight Hyaluronic Acid with Immobilized Enzyme Cascades.

Gottschalk, J., Aßmann, M., Kuballa, J., & Elling, L.
ChemSusChem, 2022
https://doi.org/10.1002/cssc.202101071

Engineering analysis of multienzyme cascade reactions for 3ʹ-sialyllactose synthesis

Schelch, S., Eibinger, M., Gross Belduma, S., Petschacher, B., Kuballa, J., & Nidetzky, B.
Biotechnology and Bioengineering, 2021
https://doi.org/10.1002/bit.27898

 

Integration of a Nucleoside Triphosphate Regeneration System in the One‐pot Synthesis of UDP‐sugars and Hyaluronic Acid

Gottschalk, J., Blaschke, L., Aßmann, M., Kuballa, J., & Elling, L.
ChemCatChem, 2021
https://doi.org/10.1002/cctc.202100462

Nmpc‐based workflow for simultaneous process and model development applied to a fed‐batch process for recombinant C. glutamicum

Levermann, P., Freiberger, F., Katha, U., Zaun, H., Möller, J., Hass, V. C., Schoop, K. M., Kuballa, J., & Pörtner, R.
Processes, 2020
https://doi.org/10.3390/pr8101313

Key factors for a one-pot enzyme cascade synthesis of high molecular weight hyaluronic acid.

Gottschalk, J., Zaun, H., Eisele, A., Kuballa, J., & Elling, L.
International Journal of Molecular Sciences, 2019
https://doi.org/10.3390/ijms20225664

In Vitro One-Pot Enzymatic Synthesis of Hyaluronic Acid from Sucrose and N-Acetylglucosamine: Optimization of the Enzyme Module System and Nucleotide Sugar Regeneration.

Eisele, A., Zaun, H., Kuballa, J., & Elling, L.
ChemCatChem, 2018
https://doi.org/10.1002/cctc.201800370

Poster

Multi-Enzyme Cascade in Packed bed Reactors for Sialyllactose Synthesis

Hölting K., Aßmann M., Bubenheim P., Liese A., Kuballa J.
Biocat 2024, Hamburg, Germany

 

Precise Genome Editing via CRISPR/Cas9 for in vivo Production of Sialyllactose

Körtje F., Aßmann M., Bubenheim P., Andreas L., Kuballa J.
Biocat 2024, Hamburg, Germany

 

Modelling of an Immobilised Enzyme Cascade in Packed Bed Reactors

Hölting K., Aßmann M., Bubenheim P., Liese A., Kuballa J.
Himmelfahrtstagung on Bioprocess Engineering 2024, Regensburg, Germany

 

CRISPR Cas9-Mediated Engineering of a Sialyllactose-Producing Strain for Whole-Cell Biocatalysis

Körtje F., Aßmann M., Bubenheim P., Andreas L., Kuballa J.
Himmelfahrtstagung on Bioprocess Engineering 2024, Regensburg, Germany

 

Whole-Cell Biocatalysis: CRISPR Cas9 for Development of a Sialyllactose-Producung Strain

Körtje F., Aßmann M., Bubenheim P., Andreas L., Kuballa J.
14th European Congress of Chemical Engineering and 7th European Congress of Applied Biotechnology 2023, Berlin, Germany

 

Polyphosphate Kinase – Enzyme Stabilization Through Immobilization

Hölting K., Götz S., Aßmann M., Bubenheim P., Liese A., Kuballa J.
14th European Congress of Chemical Engineering and 7th European Congress of Applied Biotechnology 2023, Berlin, Germany

 

A complex reaction cascade for the biocatalysis of sialyllactose

Hölting K., Aßmann M., Andrich A., Bubenheim P., Liese A., Kuballa J.
European Federation of Biotechnology 2021, virtual conference